ABACUS-R Sequence Design

Use ABACUS-R to design protein sequences for a given backbone structure using an encoder-decoder model.

ABACUS-R Sequence Design media

ABACUS-R designs sequences by predicting sidechains of a central residue based on its local three-dimensional environment. ABACUS-R predicts one high fidelity sequence that is then folded and returned.

Estimated resource cost: 0.0002945

Categories: Protein Design

Tags: Inverse Folding Proteins

Key Capabilities

  • Uses an encoder-decoder to predict sequences using local 3-dimensional structural environments.
  • Produces self-consistent sequences to a target backbone.
  • Backed by X-Ray Crystallography experiments, showing state-of-the-art performance.

Runtime Statistics

MetricValue
runtime_mean423
runtime_median371
runtime_std277
runtime_90th_percentile653
runtime_max1177

Similar Tools

  • ESM-IF1
  • LigandMPNN
  • MIF-ST
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Review your configuration, then confirm the estimated credit cost before you run the job. Note that credit estimates are not guaranteed and runtime can vary depending on inputs and settings.

Estimated Credits: 0.0002945

Invite-only, limited-time access. Please contact ztang@getantibody.com.

Invite-only, limited-time access. Please contact ztang@getantibody.com.

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