ABACUS-R Sequence Design
Use ABACUS-R to design protein sequences for a given backbone structure using an encoder-decoder model.

ABACUS-R designs sequences by predicting sidechains of a central residue based on its local three-dimensional environment. ABACUS-R predicts one high fidelity sequence that is then folded and returned.
Estimated resource cost: 0.0002945
Categories: Protein Design
Tags: Inverse Folding Proteins
Key Capabilities
- Uses an encoder-decoder to predict sequences using local 3-dimensional structural environments.
- Produces self-consistent sequences to a target backbone.
- Backed by X-Ray Crystallography experiments, showing state-of-the-art performance.
Runtime Statistics
| Metric | Value |
|---|---|
| runtime_mean | 423 |
| runtime_median | 371 |
| runtime_std | 277 |
| runtime_90th_percentile | 653 |
| runtime_max | 1177 |
Similar Tools
- ESM-IF1
- LigandMPNN
- MIF-ST
- ProteinMPNN
Ready to submit your job?
Review your configuration, then confirm the estimated credit cost before you run the job. Note that credit estimates are not guaranteed and runtime can vary depending on inputs and settings.
Estimated Credits: 0.0002945
Invite-only, limited-time access. Please contact ztang@getantibody.com.
Invite-only, limited-time access. Please contact ztang@getantibody.com.