BioFold2
Design next-generation enzymes by co-optimizing for catalytic activity, stability, and solubility.
BioFold2 leverages a state-of-the-art hybrid engine, combining generative AI with physics and evolutionary principles. This allows for the simultaneous, high-fidelity optimization of multiple enzyme properties, delivering novel candidates with unparalleled performance.
Estimated resource cost: 0.001178
Categories: Protein Design
Tags: Developability Enzymes Proteins Solubility Stability
Key Capabilities
- Powered by our proprietary BioFold2 model.
- Simultaneously optimizes for thermostability, pH stability, solubility, and catalytic reaction rate.
- Uses a hybrid architecture of AI, physics-based simulations, and evolutionary signals.
- Unlocks innovative enzyme designs with significant mutations that lead to enhanced performance.
- De-risks R&D by computationally screening thousands of variants to identify top candidates for wet-lab validation.
- Specialized for active site engineering with full awareness of ligand and substrate interactions.
Runtime Statistics
| Metric | Value |
|---|---|
| runtime_mean | 106096 |
| runtime_median | 106096 |
| runtime_std | 8710 |
| runtime_90th_percentile | 114806 |
| runtime_max | 114806 |
Similar Tools
- BioFold
- BindFilter
- Efficient Evolution
- EpHod Optimal Enzyme pH Prediction
Ready to submit your job?
Review your configuration, then confirm the estimated credit cost before you run the job. Note that credit estimates are not guaranteed and runtime can vary depending on inputs and settings.
Estimated Credits: 0.001178
Invite-only, limited-time access. Please contact ztang@getantibody.com.
Invite-only, limited-time access. Please contact ztang@getantibody.com.