BioPhi
AI-driven antibody humanization + humanness scoring from natural repertoire data.

BioPhi combines Sapiens (deep learning antibody humanization) with OASis (9-mer humanness evaluation from 231 human repertoires) to redesign non-human antibodies while quantifying immunogenicity risk.
Estimated resource cost: 0.00068882
Categories: Protein Design
Tags: Antibodies Developability Immunogenicity Other Binders Proteins
Key Capabilities
- Accepts antibodies (VH:VL), nanobodies (single domain), and scFvs (VH:VL domains) as input.
- Generates humanized sequence candidates and summary reports suitable for downstream filtering.
- Exports tool outputs (e.g., FASTA/Excel) for easy review and comparison.
Runtime Statistics
| Metric | Value |
|---|---|
| runtime_mean | 15 |
| runtime_median | 15 |
| runtime_std | 0 |
| runtime_90th_percentile | 15 |
| runtime_max | 15 |
Similar Tools
- BindFilter
- BioBind
- Humatch
- ProteinMPNN-ddG
Ready to submit your job?
Review your configuration, then confirm the estimated credit cost before you run the job. Note that credit estimates are not guaranteed and runtime can vary depending on inputs and settings.
Estimated Credits: 0.00068882
Invite-only, limited-time access. Please contact ztang@getantibody.com.
Invite-only, limited-time access. Please contact ztang@getantibody.com.