Chai-1 (AlphaFold3)

Commercial friendly alternative to AlphaFold3 with competitive MSA-less option.

Chai-1 (AlphaFold3) media

Chai-1 is an advanced open-source model delivering AlphaFold3-level accuracy in predicting 3D structures of biomolecular complexes. The model integrates state-of-the-art innovations in architecture, MSA processing, and interaction confidence scoring. Chai-1 provides accessible tools for structural biology and drug discovery.

Estimated resource cost: 0.0024025

Categories: Structure Prediction & Folding

Tags: Co-Folding Conformation Generation Nucleotides Protein Folding Proteins Protein–Ligand Docking Protein–Protein Docking Small Molecules

Key Capabilities

  • Delivers AlphaFold3-level accuracy for biomolecular structure prediction.
  • Handles diverse molecular systems: proteins, RNA/DNA, and small molecules.
  • Cutting-edge approaches for MSA pairing and structural conditioning.
  • Optimized for efficient, accurate confidence predictions in molecular interactions.
  • Demonstrates superior computational efficiency and speed over previous models.
  • Validated extensively on CASP15 and specialized benchmarking datasets.

Runtime Statistics

MetricValue
runtime_mean223
runtime_median110
runtime_std637
runtime_90th_percentile494
runtime_max37260

Similar Tools

  • Boltz-1 (AlphaFold3)
  • Boltz-2 (AlphaFold3)
  • IntelliFold (AlphaFold3)
  • OpenFold3 (AlphaFold3)
Job submission preview

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Review your configuration, then confirm the estimated credit cost before you run the job. Note that credit estimates are not guaranteed and runtime can vary depending on inputs and settings.

Estimated Credits: 0.0024025

Invite-only, limited-time access. Please contact ztang@getantibody.com.

Invite-only, limited-time access. Please contact ztang@getantibody.com.

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