Efficient Evolution
A protein language model-based tool for efficient, task-agnostic design of high-functionality protein variants.
Efficient Evolution leverages general protein language models to guide the efficient evolution of proteins. These models utilize evolutionary-scale data to recommend mutations that are evolutionarily plausible and likely to enhance protein functionality. By operating in sequence space without requiring knowledge of target-specific details, Efficient Evolution streamlines the design process. It generates small, high-confidence variant sets for experimental validation, offering a scalable and task-agnostic solution for protein engineering applications.
Estimated resource cost: 0.000527
Categories: Protein Design
Tags: Developability Mutational Scanning Proteins Solubility Stability
Key Capabilities
- Offers a general-purpose approach applicable across diverse protein families.
- Utilizes evolutionary-scale data to recommend plausible and functional mutations.
- Facilitates the exploration of sequence space while maintaining evolutionary plausibility.
Runtime Statistics
| Metric | Value |
|---|---|
| runtime_mean | 65 |
| runtime_median | 61 |
| runtime_std | 26 |
| runtime_90th_percentile | 70 |
| runtime_max | 380 |
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Review your configuration, then confirm the estimated credit cost before you run the job. Note that credit estimates are not guaranteed and runtime can vary depending on inputs and settings.
Estimated Credits: 0.000527
Invite-only, limited-time access. Please contact ztang@getantibody.com.
Invite-only, limited-time access. Please contact ztang@getantibody.com.