ESM-IF1

Predict alternative sequences for an input protein structure with high accuracy.

ESM-IF1 media

The ESM-IF1 inverse folding model predicts protein sequences from their backbone atom coordinates, trained with 12M protein structures predicted by AlphaFold2.

Estimated resource cost: 0.0002945

Categories: Protein Design

Tags: Inverse Folding Proteins

Key Capabilities

  • Allows you to inverse fold any protein or complex of proteins.
  • Includes options to control which chains to design and which to keep fixed.
  • Supports different sampling techniques to better explore the protein landscape.
  • Includes per sequence metrics such as an overall score and sequence recovery.
  • Includes amino acid probabilities by position.

Runtime Statistics

MetricValue
runtime_mean449
runtime_median39
runtime_std2092
runtime_90th_percentile728
runtime_max32469

Similar Tools

  • ABACUS-R Sequence Design
  • LigandMPNN
  • MIF-ST
  • ProteinMPNN
Job submission preview

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Review your configuration, then confirm the estimated credit cost before you run the job. Note that credit estimates are not guaranteed and runtime can vary depending on inputs and settings.

Estimated Credits: 0.0002945

Invite-only, limited-time access. Please contact ztang@getantibody.com.

Invite-only, limited-time access. Please contact ztang@getantibody.com.

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