USalign Structural Alignment
Efficiently produce accurate 3D structural alignments across diverse macromolecular forms and configurations
US-align is a unified tool for comparing 3D structures of proteins, RNAs, and DNAs across various configurations (monomers, oligomers, and heterocomplexes) for pairwise and multiple alignments. It builds on TM-align, optimizing structural alignment through heuristic dynamic programming to maximize TM-score. Benchmark tests show that US-align achieves high accuracy with reduced CPU time compared to specialized alignment methods.
Estimated resource cost: 0.000062
Categories: Utilities & Conversions
Tags: Proteins Structural Alignment
Key Capabilities
- Performs 3D structure alignments for monomeric and complex structures of proteins, RNAs, and DNAs.
- Utilizes a unified TM-score objective function for improved alignment accuracy and speed.
- Optimized for fast and accurate alignment of complex oligomers and large macromolecular structures.
- Includes a heuristic iterative searching algorithm to avoid local minima in alignments.
Runtime Statistics
| Metric | Value |
|---|---|
| runtime_mean | 21 |
| runtime_median | 8 |
| runtime_std | 30 |
| runtime_90th_percentile | 80 |
| runtime_max | 265 |
Similar Tools
- LDDT Structural Comparison
- ClusterProt
- Foldseek Structural Clustering
- Kluster
Ready to submit your job?
Review your configuration, then confirm the estimated credit cost before you run the job. Note that credit estimates are not guaranteed and runtime can vary depending on inputs and settings.
Estimated Credits: 0.000062
Invite-only, limited-time access. Please contact ztang@getantibody.com.
Invite-only, limited-time access. Please contact ztang@getantibody.com.